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Invitrogen
Coronin 1B Polyclonal Antibody
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Product Details
PA5-111118
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Coronin 1B. Recombinant protein control fragment (Product #RP-103764).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AYVPSKQRDL KISRRNVLSD SRPAMAPGSS HLGAPASTTT AAGATPSGSL ARAGEAGKLE EVMQELRALR ALVKEQGDRI CRLEEQLGRM ENGD
Highest antigen sequence indentity to the following orthologs: Mouse - 78%, Rat - 76%.
Target Information
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coronin, actin binding protein, 1B; Coronin-1B; Coronin-2; unnamed protein product
Gene Aliases: CORO1B; CORONIN-2
UniProt ID: (Human) Q9BR76
Entrez Gene ID: (Human) 57175
actin filament organization
cell migration
actin cytoskeleton organization
ruffle organization
regulation of Arp2/3 complex-mediated actin nucleation
negative regulation of Arp2/3 complex-mediated actin nucleation
endothelial cell chemotaxis
cellular response to platelet-derived growth factor stimulus
wound healing
actin filament bundle assembly
negative regulation of cellular component organization
negative regulation of smooth muscle cell chemotaxis
actin filament branching
protein localization to cell leading edge
positive regulation of lamellipodium morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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