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Invitrogen
PAF1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-111143
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EVMPVFPDFK MWINPCAQVI FDSDPAPKDT SGAAALEMMS QAMIRGMMDE EGNQFVAYFL PVEETLKKRK RDQEEEMDYA PDDVY
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
靶标信息
This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPAF1; Paf1, RNA polymerase II associated factor, homolog; Pancreatic differentiation protein 2; RNA polymerase II-associated factor 1 homolog; unnamed protein product
基因别名: F23149_1; PAF1; PD2
UniProt ID: (Human) Q8N7H5
Entrez Gene ID: (Human) 54623
negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate commitment
transcription elongation from RNA polymerase II promoter
Wnt signaling pathway
stem cell population maintenance
mRNA 3'-end processing
protein localization to nucleus
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
positive regulation of cell cycle G1/S phase transition
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