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Invitrogen
GNAI1 Polyclonal Antibody
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Product Details
PA5-111148
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human GNAI1. Recombinant protein control fragment (Product #RP-105611).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ARQLFVLAGA AEEGFMTAEL AGVIKR
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain; and transducin-1 and transducin-2, proteins involved in phototransduction in retinal rods and cones, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate cyclase-inhibiting G alpha protein; G protein; Gi1 protein alpha subunit; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide-binding protein alpha-i subunit; Guanine nucleotide-binding protein G(i) subunit alpha-1; heterotrimeric guanine nucleotide-binding protein 1B; unnamed protein product
Gene Aliases: Gi; GNAI1; HG1B; NEDHISB
UniProt ID: (Human) P63096
Entrez Gene ID: (Human) 2770
nucleotide binding
magnesium ion binding
G-protein coupled receptor binding
GTPase activity
obsolete small monomeric GTPase activity
protein binding
GTP binding
adenylate cyclase regulator activity
adenylate cyclase inhibitor activity
hydrolase activity
guanyl nucleotide binding
GDP binding
G-protein beta/gamma-subunit complex binding
D2 dopamine receptor binding
G-protein coupled serotonin receptor binding
metal ion binding
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
neuropeptide signaling pathway
response to prostaglandin E
response to peptide hormone
positive regulation of cholesterol biosynthetic process
negative regulation of insulin secretion
cell division
regulation of mitotic spindle organization
chemokine-mediated signaling pathway
T cell migration
positive regulation of relaxation of smooth muscle
cellular response to forskolin
positive regulation of protein localization to cell cortex
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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