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Invitrogen
Jagged2 Polyclonal Antibody
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Product Details
PA5-111319
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Jagged2. Recombinant protein control fragment (Product #RP-106291).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTLHFNRDHV PQGTTVGAIC SGIRSLPATR AVARDRLLVL LCDRASSGAS AVEVAVSFSP ARDLPDSSLI QGAAHAIVAA ITQRGNSSLL LAVTEVKVET VVTG
Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 91%.
Target Information
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Jagged2; Protein jagged-2
Gene Aliases: HJ2; JAG2; SER2
UniProt ID: (Human) Q9Y219
Entrez Gene ID: (Human) 3714
skeletal system development
in utero embryonic development
respiratory system process
cell cycle
Notch signaling pathway
Notch receptor processing
spermatogenesis
auditory receptor cell fate commitment
morphogenesis of embryonic epithelium
cell differentiation
regulation of cell adhesion
T cell differentiation
regulation of cell migration
regulation of cell proliferation
odontogenesis of dentin-containing tooth
gamma-delta T cell differentiation
thymic T cell selection
positive regulation of Notch signaling pathway
epithelial cell apoptotic process involved in palatal shelf morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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