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Invitrogen
FABP3 Polyclonal Antibody
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Product Details
PA5-111425
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human FABP3. Recombinant protein control fragment (Product #RP-101744).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TRQVASMTKP TTIIEKNGDI LTLKTHSTF
Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 86%.
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 422 protein; Cardiac Fatty Acid Binding Protein; epididymis secretory sperm binding protein; FABP 3; FABP3; fatty acid binding protein 11; Fatty acid binding protein 11 (FABP11); fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; Fatty acid-binding protein 3; Fatty acid-binding protein, heart; H-FABP; heart FABP; Heart type fatty acid binding protein; Heart-type fatty acid-binding protein; M FABP; M-FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte; unnamed protein product
Gene Aliases: FABP11; FABP3; H-FABP; M-FABP; MDGI; O-FABP
UniProt ID: (Human) P05413
Entrez Gene ID: (Human) 2170
fatty acid metabolic process
negative regulation of cell proliferation
response to xenobiotic stimulus
long-chain fatty acid transport
intracellular lipid transport
response to insulin
cholesterol homeostasis
regulation of fatty acid oxidation
brown fat cell differentiation
phospholipid homeostasis
response to fatty acid
positive regulation of phospholipid biosynthetic process
positive regulation of long-chain fatty acid import into cell
regulation of phosphatidylcholine biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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