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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ATG4A Antibodies

          Invitrogen

          ATG4A Polyclonal Antibody

          View all (19) ATG4A antibodies

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          Cite ATG4A Polyclonal Antibody

          • Antibody Testing Data (2)
          ATG4A Antibody in Immunocytochemistry (ICC/IF)
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          ATG4A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          ATG4A Antibody (PA5-111588) in ICC/IF

          Immunofluorecent analysis of ATG4A in human cell line PC-3 using ATG4A Polyclonal Antibody (Product # PA5-111588). Staining shows localization to microtubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ATG4A Antibody in Immunocytochemistry (ICC/IF)
          ATG4A Antibody in Western Blot (WB)
          ATG4A Polyclonal Antibody

          Product Details

          PA5-111588

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein corresonding to Human ATG4A. Recombinant protein control fragment (Product #RP-105342).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2856998

          Product Specific Information

          Immunogen sequence: ESVLSKYEDQ ITIFTDYLEE YPDTDELVWI LGKQHLLKTE KSKLLSDISA RLWFTYRRKF SPIGGTG

          Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 91%.

          Target Information

          Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; Autophagin-2; autophagy related 4A, cysteine peptidase; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; Cysteine protease ATG4A; hAPG4A; HsAPG4A; MGC107179

          View more View less

          Gene Aliases: APG4A; ATG4A; AUTL2

          View more View less

          UniProt ID: (Human) Q8WYN0

          View more View less

          Entrez Gene ID: (Human) 115201

          View more View less

          Function(s)
          cysteine-type endopeptidase activity protein binding cysteine-type peptidase activity cysteine protease
          Process(es)
          autophagosome assembly mitophagy C-terminal protein lipidation proteolysis protein targeting to membrane protein processing nucleophagy protein delipidation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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