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Invitrogen
COL7A1 Polyclonal Antibody
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Product Details
PA5-139764
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human COL7A1. Recombinant protein control fragment (Product #RP-102926).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: LTLYTLLEGH EVATPATVVP TGPELPVSPV TDLQATELPG QRVRVSWSPV PGATQYRIIV RSTQGVERTL VLPGSQTAFD LDDVQAGLSY TVRVSARVGP REGSASVLTV RREPETPLAV PGLRVVVSDA TRVRVAWGPA PGASGFRI
Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 76%.
Target Information
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagen alpha-1(VII) chain; collagen vii; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; HGNC:2214; LC collagen; long chain collagen; Long-chain collagen
Gene Aliases: COL7A1; EBD1; EBDCT; EBR1; NDNC8
UniProt ID: (Human) Q02388
Entrez Gene ID: (Human) 1294
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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