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          • Primary Antibodies ›
          • Histone H1.1 Antibodies

          Invitrogen

          Histone H1.1 Polyclonal Antibody

          View all (7) Histone H1.1 antibodies

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          Cite Histone H1.1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          Histone H1.1 Antibody in Immunocytochemistry (ICC/IF)
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          Histone H1.1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Histone H1.1 Antibody (PA5-139832) in ICC/IF

          Immunofluorecent analysis of Histone H1.1 in human cell line U-2 OS using Histone H1.1 Polyclonal Antibody (Product # PA5-139832). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Histone H1.1 Antibody in Immunocytochemistry (ICC/IF)
          Histone H1.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Histone H1.1 Polyclonal Antibody

          Product Details

          PA5-139832

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human H1-1. Recombinant protein control fragment (Product #RP-108931).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2926834

          Product Specific Information

          Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

          Immunogen sequence: PAKAAAASKK KPAGPSVSEL IVQAASSSKE RG

          Highest antigen sequence indentity to the following orthologs: Rat - 81%, Mouse - 84%.

          Target Information

          Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: H1 histone family, member 1; histone 1, H1a; histone cluster 1 H1 family member a; histone cluster 1, H1a; Histone H1.1; Histone H1a

          View more View less

          Gene Aliases: H1-1; H1.1; H1A; H1F1; HIST1; HIST1H1A

          View more View less

          UniProt ID: (Human) Q02539

          View more View less

          Entrez Gene ID: (Human) 3024

          View more View less

          Function(s)
          DNA binding double-stranded DNA binding protein binding heparin binding structural constituent of chromatin chromatin DNA binding nucleosomal DNA binding
          Process(es)
          nucleosome assembly spermatogenesis chromosome condensation negative regulation of DNA recombination positive regulation of receptor-mediated endocytosis
          It has to be done as per old AB suggested Products section.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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