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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: ILRFYTAQDG TDWLRAVSAN IRELTLQNMK MANKCCSPSD QVVHMGWVNE KLQGADSSQT FRPKFLALK
Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 77%.
Syntrophin gamma 2 encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G2SYN; Gamma-2-syntrophin; gamma2-syntrophin; MGC133174; SYN5; syntrophin; syntrophin 5; Syntrophin-5
Gene Aliases: SNTG2
Entrez Gene ID: (Human) 54221
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