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Invitrogen
PPP1R3A Polyclonal Antibody
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FIGURE: 1 / 3
PPP1R3A Antibody (PA5-139975) in IHC (P)
Immunohistochemical analysis of PPP1R3A in human skeletal muscle and smooth muscle tissues using PPP1R3A Polyclonal Antibody (Product # PA5-139975) using Anti-PPP1R3A antibody. Corresponding PPP1R3A RNA-seq data are presented for the same tissues.
Product Details
PA5-139975
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPP1R3A. Recombinant protein control fragment (Product #RP-109209).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: CNSTREIQGI EKHPYPESKP EEVSRSSGIV TSGSRKERCI GQIFQTEEYS VEKSLGPMIL INKPLENMEE ARHENEGLVS SGQSLYTSGE KESDSSASTS LPVEESQAQG NESLFS
Highest antigen sequence indentity to the following orthologs: Mouse - 46%, Rat - 52%.
Target Information
PPP1R3A, the glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. PPP1R3A encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle; glycogen-associated regulatory subunit of protein phosphatase-1; protein phosphatase 1 glycogen- associated regulatory subunit; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase 1 regulatory subunit 3A; protein phosphatase 1 regulatory subunit GM; protein phosphatase 1, regulatory (inhibitor) subunit 3A; protein phosphatase 1, regulatory subunit 3A; Protein phosphatase type-1 glycogen targeting subunit; RG1; serine /threonine specific protein phosphatase; type-1 protein phosphatase skeletal muscle glycogen targeting subunit
Gene Aliases: GM; PP1G; PPP1R3; PPP1R3A
UniProt ID: (Human) Q16821
Entrez Gene ID: (Human) 5506
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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