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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PGFLNGSPTG SPYGIMSSSP TVGSSSTSSI LPF
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Early B-cell factor 2 (EBF2) is a gene located on chromosome 8p11.23, encoding a transcription factor involved in the regulation of gene expression during neural and adipose tissue development. EBF2 belongs to the COE family of transcription factors and plays a pivotal role in cellular differentiation processes. In the nervous system, EBF2 is essential for the development and function of neurons, particularly in regions like the olfactory system. Additionally, EBF2 is involved in adipogenesis, where it regulates genes responsible for the differentiation of brown adipocytes, contributing to thermogenesis and energy metabolism. Dysfunction or altered expression of EBF2 can impact neurological function and metabolic homeostasis, potentially influencing conditions such as obesity, diabetes, and neurodevelopmental disorders. Research into EBF2 is exploring its role in these physiological contexts and the implications of its regulatory mechanisms, offering insights into potential therapeutic approaches.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collier, Olf and EBF 2; Early B-cell factor 2; EBF-2; metencephalon-mesencephalnon-olfactory transcription factor 1; OLF-1/EBF-LIKE 3; Transcription factor COE2
Gene Aliases: COE2; EBF-2; EBF2; O/E-3; OE-3
UniProt ID: (Human) Q9HAK2
Entrez Gene ID: (Human) 64641
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