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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • THEM2 Antibodies

          Invitrogen

          THEM2 Polyclonal Antibody

          View all (8) THEM2 antibodies

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          Cite THEM2 Polyclonal Antibody

          • Antibody Testing Data (4)
          THEM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          THEM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          THEM2 Antibody (PA5-140225) in IHC (P)

          Immunohistochemical analysis of THEM2 in human liver and tonsil tissues using THEM2 Polyclonal Antibody (Product # PA5-140225) using Anti-ACOT13 antibody. Corresponding ACOT13 RNA-seq data are presented for the same tissues. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          THEM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          THEM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          THEM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          THEM2 Antibody in Western Blot (WB)
          THEM2 Polyclonal Antibody

          Product Details

          PA5-140225

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ACOT13. Recombinant protein control fragment (Product #RP-108938).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2927227

          Product Specific Information

          Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

          Immunogen sequence: LGKITLVSAA PGKVICEMKV EEEHTNAIGT LHGGLTATLV DNISTMALLC TER

          Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 83%.

          Target Information

          THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Acyl-CoA thioesterase 13; Acyl-coenzyme A thioesterase 13; Hotdog-fold thioesterase superfamily member 2; hypothalamus protein HT012; Palmitoyl-CoA hydrolase; THEM2; Thioesterase superfamily member 2

          View more View less

          Gene Aliases: ACOT13; HT012; PNAS-27; THEM2

          View more View less

          UniProt ID: (Human) Q9NPJ3

          View more View less

          Entrez Gene ID: (Human) 55856

          View more View less

          Function(s)
          acyl-CoA hydrolase activity esterase hydrolase metabolite interconversion enzyme
          Process(es)
          long-chain fatty-acyl-CoA biosynthetic process protein homotetramerization
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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