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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: KYISLNDLQQ VKDRGPVVSL WPAPGKHSEI YNKLSTVEHM TVYEKEAIPS RFYYKKGKFV SPLTLVADEG WFITENREML PFWMNSTGRR EGWQRG
Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 88%.
Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B830047L21Rik; choline-specific glycerophosphodiester phosphodiesterase; E-NPP 6; ectonucleotide pyrophosphatase/phosphodiesterase family member 6; GPC-Cpde; NPP-6; unnamed protein product
Gene Aliases: NPP6
UniProt ID: (Human) Q6UWR7
Entrez Gene ID: (Human) 133121
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