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Invitrogen
DOCK8 Polyclonal Antibody
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Product Details
PA5-140262
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DOCK8. Recombinant protein control fragment (Product #RP-109342).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: INRYSSAEIR KQFTLPPNLG QYHRQSISTS GFPSLQLPQF YDPVEPVDFE GLLMTHLNSL DVQLAQELGD FTDDDLDVVF
Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 86%.
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1200017A24Rik; Dedicator of cytokinesis protein 8; epididymis luminal protein 205
Gene Aliases: DOCK8; HEL-205; MRD2; ZIR8
UniProt ID: (Human) Q8NF50
Entrez Gene ID: (Human) 81704
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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