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Invitrogen
MCAK Polyclonal Antibody
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Product Details
PA5-140304
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KIF2C. Recombinant protein control fragment (Product #RP-109690).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: MDSSLQARLF PGLAIKIQRS NGLIHSANVR TVNLEKSCVS VEWAEGGATK GKEIDFDDVA AINPELLQLL PLHPKDNLPL QENVTIQK
Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 81%.
Target Information
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsMCAK; KIF2C; Kinesin-like protein 6; Kinesin-like protein KIF2C; MCAK; Mitotic centromere-associated kinesin; RP11-269F19.1; testis tissue sperm-binding protein Li 68n; TS-MSAK; unnamed protein product
Gene Aliases: CT139; KIF2C; KNSL6; MCAK
UniProt ID: (Human) Q99661
Entrez Gene ID: (Human) 11004
mitotic sister chromatid segregation
microtubule-based movement
microtubule depolymerization
chromosome segregation
mitotic metaphase plate congression
establishment or maintenance of microtubule cytoskeleton polarity
cell division
metaphase plate congression
attachment of mitotic spindle microtubules to kinetochore
regulation of chromosome segregation
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
postsynaptic cytoskeleton organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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