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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PVSRCQRLSE LYLRRNRIPS LAELFYLKGL PRLRVLWLAE NPCCGTSPHR YRMTVLRTLP RLQKLDNQAV TEEELSRALS EGEEITAA
Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 85%.
Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C21orf-HUMF09G8.5; cDNA A2-YF5; Cilia- and flagella-associated protein 410; cu002; Leucine-rich repeat-containing protein 76; YF5; YF5/A2
Gene Aliases: C21orf2; CFAP410; LRRC76
Entrez Gene ID: (Human) 755
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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