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Invitrogen
Tenascin X Polyclonal Antibody
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Product Details
PA5-144719
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 55-173. Recombinant protein control fragment (Product #RP-109980).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PSSQLYEHTV EGGEKQVVFT HRINLPPSTG CGCPPGTEPP VLASEVQALR VRLEILEELV KGLKEQCTGG CCPASAQAGT GQTDVRTLCS LHGVFDLSRC TCSCEPGWGG PTCSDPTDA
Antigen sequence identity: Mouse 92%; Rat 47%
Target Information
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GIG45; growth-inhibiting protein 45; Hexabrachion-like protein; tenascin XB1; tenascin XB2; Tenascin-X; TN-X; TNXB2tenascin XB1; TNXBSTNXTENX; unidentified protein; XB-S; XBTN-X
Gene Aliases: EDS3; EDSCLL; EDSCLL1; HXBL; TENX; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
UniProt ID: (Human) P22105
Entrez Gene ID: (Human) 7148
lipid metabolic process
fatty acid metabolic process
triglyceride metabolic process
cell adhesion
cell-matrix adhesion
positive regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
actin cytoskeleton organization
regulation of cell adhesion
extracellular matrix organization
collagen fibril organization
regulation of cell migration
neuron projection development
collagen metabolic process
regulation of cell differentiation
regulation of JNK cascade
elastic fiber assembly
cell-cell adhesion
positive regulation of vascular endothelial growth factor signaling pathway
positive regulation of collagen fibril organization
positive regulation of cell fate determination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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