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Invitrogen
HDAC10 Polyclonal Antibody
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Product Details
PA5-144723
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 416-545. Recombinant protein control fragment (Product #RP-110180).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTTPDITLVL PPDVIQQEAS ALREETEAWA RPHESLAREE ALTALGKLLY LLDGMLDGQV NSGIAATPAS AAAATLDVAV RRGLSHGAQR LLCVALGQLD RPPDLAHDGR SLWLNIRGKE AAALSMFHVS
Antigen sequence identity: Mouse 64%; Rat 51%
Target Information
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; dJ402G11.7; DKFZp761B039; HD10; HDAC10b; Histone deacetylase 10; MGC149722; Polyamine deacetylase HDAC10; related to Hda1; RP3-402G11.7
Gene Aliases: HD10; HDAC10
UniProt ID: (Human) Q969S8
Entrez Gene ID: (Human) 83933
negative regulation of transcription from RNA polymerase II promoter
DNA repair
DNA recombination
chromatin organization
regulation of transcription, DNA-templated
autophagy
cellular response to DNA damage stimulus
macroautophagy
positive regulation of mismatch repair
reciprocal DNA recombination
negative regulation of transcription, DNA-templated
macromolecule deacylation
polyamine deacetylation
spermidine deacetylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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