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Invitrogen
STAP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-144867
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 210-286. Recombinant protein control fragment (Product #RP-110001).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NYSITIRQEI DIPRIKHYKV MSVGQNYTIE LEKPVTLPNL FSVIDYFVKE TRGNLRPFIC STDENTGQEP SMEGRSE
Antigen sequence identity: Mouse 81%; Rat 82%
Target Information
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCR downstream-signaling protein 1; docking protein BRDG1; stem cell adaptor protein 1; unnamed protein product
Gene Aliases: BRDG1; STAP-1
UniProt ID: (Human) Q9ULZ2
Entrez Gene ID: (Human) 26228
phosphotyrosine binding
transmembrane receptor protein tyrosine kinase adaptor activity
macrophage colony-stimulating factor receptor binding
protein binding
phospholipid binding
protein kinase binding
protein tyrosine kinase activator activity
protein binding, bridging
receptor tyrosine kinase binding
signaling adaptor activity
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of gene expression
negative regulation of macrophage chemotaxis
positive regulation of B cell receptor signaling pathway
positive regulation of phagocytosis, engulfment
cellular response to lipopolysaccharide
negative regulation of ruffle assembly
negative regulation of macrophage colony-stimulating factor signaling pathway
positive regulation of microglial cell activation
negative regulation of microglial cell migration
positive regulation of microglial cell mediated cytotoxicity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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