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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Pirin Antibodies

          Invitrogen

          Pirin Polyclonal Antibody

          View all (9) Pirin antibodies

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          Cite Pirin Polyclonal Antibody

          • Antibody Testing Data (2)
          Pirin Antibody in Immunocytochemistry (ICC/IF)
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          Pirin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Pirin Antibody (PA5-145092) in ICC/IF

          Immunocytochemistry analysis of Pirin in U2OS cells. Samples were incubated with Pirin polyclonal antibody (Product # PA5-145092). Shows localization to nucleoplasm & cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Pirin Antibody in Immunocytochemistry (ICC/IF)
          Pirin Antibody in Western Blot (WB)
          Pirin Polyclonal Antibody

          Product Details

          PA5-145092

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 192-287. Recombinant protein control fragment (Product #RP-109869).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3091765

          Product Specific Information

          Immunogen sequence: SFIYTISGDV YIGPDDAQQK IEPHHTAVLG EGDSVQVENK DPKRSHFVLI AGEPLREPVI QHGPFVMNTN EEISQAILDF RNAKNGFERA KTWKSK

          Antigen sequence identity: Mouse 95%; Rat 94%

          Target Information

          This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Pirin; pirin (iron-binding nuclear protein); pirinin; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase

          View more View less

          Gene Aliases: PIR

          View more View less

          UniProt ID: (Human) O00625

          View more View less

          Entrez Gene ID: (Human) 8544

          View more View less

          Function(s)
          transcription cofactor activity protein binding quercetin 2,3-dioxygenase activity metal ion binding transcription cofactor gene-specific transcriptional regulator
          Process(es)
          regulation of transcription, DNA-templated transcription from RNA polymerase II promoter monocyte differentiation oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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