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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CBX6 Antibodies

          Invitrogen

          CBX6 Polyclonal Antibody

          View all (11) CBX6 antibodies

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          Cite CBX6 Polyclonal Antibody

          • Antibody Testing Data (1)
          CBX6 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          CBX6 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CBX6 Antibody (PA5-145104) in ICC/IF

          Immunocytochemistry analysis of CBX6 in HaCaT cells. Samples were incubated with CBX6 polyclonal antibody (Product # PA5-145104). Shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CBX6 Antibody in Immunocytochemistry (ICC/IF)
          CBX6 Polyclonal Antibody

          Product Details

          PA5-145104

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 271-337. Recombinant protein control fragment (Product #RP-109962).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3091877

          Product Specific Information

          Immunogen sequence: RSSGSSGCPS PTPQSSDPDD TPPKLLPETV SPSAPSWREP EVLDLSLPPE SAATSKRAPP EVTAAAG

          Antigen sequence identity: Mouse 75%; Rat 78%

          Target Information

          Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: chromobox homolog 6; Chromobox protein homolog 6

          View more View less

          Gene Aliases: CBX6

          View more View less

          UniProt ID: (Human) O95503

          View more View less

          Entrez Gene ID: (Human) 23466

          View more View less

          Function(s)
          single-stranded RNA binding protein binding chromatin/chromatin-binding, or -regulatory protein
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated covalent chromatin modification
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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