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Invitrogen
KV1.6 (KCNA6) Polyclonal Antibody
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Product Details
PA5-145136
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 473-522. Recombinant protein control fragment (Product #RP-110023).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EQGQYTHVTC GQPAPDLRAT DNGLGKPDFP EANRERRPSY LPTPHRAYAE
Antigen sequence identity: Mouse 92%; Rat 90%
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ25134; human brain potassium channel-2; potassium channel, voltage gated shaker related subfamily A, member 6; Potassium voltage-gated channel subfamily A member 6; potassium voltage-gated channel, shaker-related subfamily, member 6; protein phosphatase 1, regulatory subunit 96; Voltage-gated potassium channel HBK2; voltage-gated potassium channel protein Kv1.6; Voltage-gated potassium channel subunit Kv1.6
Gene Aliases: HBK2; KCNA6; KV1.6; PPP1R96
UniProt ID: (Human) P17658
Entrez Gene ID: (Human) 3742
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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