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          • Primary Antibodies ›
          • VSX1 Antibodies

          Invitrogen

          VSX1 Polyclonal Antibody

          View all (5) VSX1 antibodies

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          Cite VSX1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          VSX1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          VSX1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          VSX1 Antibody (PA5-145225) in ICC/IF

          Immunocytochemistry analysis of VSX1 in U2OS cells. Samples were incubated with VSX1 polyclonal antibody (Product # PA5-145225). Shows localization to nucleoli. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          VSX1 Antibody in Immunocytochemistry (ICC/IF)
          VSX1 Polyclonal Antibody

          Product Details

          PA5-145225

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 131-166. Recombinant protein control fragment (Product #RP-110239).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3092219

          Product Specific Information

          Immunogen sequence: RQKRSDSVST SDEDSQSEDR NDLKASPTLG KRTKRR

          Antigen sequence identity: Mouse 67%; Rat 64%

          Target Information

          VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in VSX1 can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Homeodomain protein RINX; Retinal inner nuclear layer homeobox protein; Transcription factor VSX1; Visual system homeobox 1; visual system homeobox 1 homolog, CHX10-like; VSX1

          View more View less

          Gene Aliases: CAASDS; KTCN; KTCN1; PPCD; PPCD1; PPD; RINX; VSX1

          View more View less

          UniProt ID: (Human) Q9NZR4

          View more View less

          Entrez Gene ID: (Human) 30813

          View more View less

          Function(s)
          transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding sequence-specific double-stranded DNA binding
          Process(es)
          regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter visual perception neuron maturation neuron development retinal bipolar neuron differentiation
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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