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Invitrogen
PLOD3 Polyclonal Antibody
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Product Details
PA5-51546
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLOD3. Recombinant protein control fragment (Product #RP-94769).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FDRNRVRIRN VAYDTLPIVV HGNGPTKLQL NYLGNYVPNG WTPEGGCGFC NQDRRTLPGG QPPPRVFLAV FVEQPTPFLP RFLQRLLLLD YPPDRVTLFL HNNEVFHEPH IADSWPQLQD HFSAVKLVGP EEAL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
Target Information
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: lysine hydroxylase 3; lysyl hydroxlase 3; lysyl hydroxylase 3; Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; unnamed protein product
Gene Aliases: BCARD; LH3; PLOD3
UniProt ID: (Human) O60568
Entrez Gene ID: (Human) 8985
catalytic activity
iron ion binding
protein binding
procollagen-lysine 5-dioxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
transferase activity
transferase activity, transferring glycosyl groups
L-ascorbic acid binding
procollagen glucosyltransferase activity
small molecule binding
metal ion binding
procollagen galactosyltransferase activity
dioxygenase activity
in utero embryonic development
endothelial cell morphogenesis
protein O-linked glycosylation
protein localization
peptidyl-lysine hydroxylation
neural tube development
collagen fibril organization
collagen metabolic process
vasodilation
hydroxylysine biosynthetic process
epidermis morphogenesis
lung morphogenesis
basement membrane assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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