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Invitrogen
MYH6 Polyclonal Antibody
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Product Details
PA5-51564
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYBPC2. Recombinant protein control fragment (Product #RP-89003).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QVEEDKVNSL SKSKVKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESIMDLE NDKLQLEEKL KKKEFDINQQ NSKIEDEQVL ALQLQKKLKE NQARIEELEE ELEAERTARA KVEKLRSDLS RELEEISERL EEA
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Target Information
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-myosin heavy chain; MyHC-alpha; myosin 6; Myosin heavy chain 6; Myosin heavy chain, cardiac muscle alpha isoform; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); Myosin-6
Gene Aliases: alpha-MHC; ASD3; CMD1EE; CMH14; MYH6; MYHC; MYHCA; SSS3
UniProt ID: (Human) P13533
Entrez Gene ID: (Human) 4624
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle system process
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
regulation of blood pressure
cardiac muscle hypertrophy in response to stress
actin filament-based movement
muscle filament sliding
myofibril assembly
sarcomere organization
ATP metabolic process
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle cell development
cardiac muscle contraction
regulation of heart growth
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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