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Invitrogen
Carbonic Anhydrase II Polyclonal Antibody
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FIGURE: 1 / 13
Carbonic Anhydrase II Antibody (PA5-51598) in ICC/IF
Immunofluorescence analysis of Carbonic Anhydrase II was performed using 70% confluent log phase A-431 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Carbonic Anhydrase II Polyclonal Antibody (Product # PA5-51598) at 1:100 dilution in 0.1% BSA, i... View More
Product Details
PA5-51598
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Carbonic Anhydrase II. Recombinant protein control fragment (Product #RP-95151).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YGKHNGPEHW HKDFPIAKGE RQSPVDIDTH TAKYDPSLKP LSVSYDQATS LRILNNGHAF NVEFDDSQDK AVLKGGPLDG TYRLIQFHFH WGSLDGQGSE HTVDKKKYAA ELHLVHWNTK YGDFGKAVQQ PDGLAVLG
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
Target Information
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CA II; CA-II; CAC; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; Cyanamide hydratase CA2; epididymis luminal protein 76; epididymis secretory protein Li 282
Gene Aliases: AI131712; CA-II; CA2; CAC; CAII; Car-2; Car2; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
UniProt ID: (Human) P00918, (Mouse) P00920, (Rat) P27139
Entrez Gene ID: (Human) 760, (Mouse) 12349, (Rat) 54231
morphogenesis of an epithelium
one-carbon metabolic process
regulation of pH
carbon dioxide transport
positive regulation of synaptic transmission, GABAergic
positive regulation of cellular pH reduction
angiotensin-activated signaling pathway
regulation of anion transport
positive regulation of osteoclast differentiation
positive regulation of bone resorption
secretion
regulation of intracellular pH
positive regulation of dipeptide transmembrane transport
regulation of chloride transport
kidney development
response to pH
response to zinc ion
bicarbonate transport
odontogenesis of dentin-containing tooth
response to estrogen
response to steroid hormone
cellular response to fluid shear stress
response to organic substance
osteoclast differentiation
regulation of cellular pH
regulation of bone resorption
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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