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Invitrogen
CYB5R3 Polyclonal Antibody
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Product Details
PA5-51601
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CYB5R3. Recombinant protein control fragment (Product #RP-91345).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SGLLVYQGKG KFAIRPDKKS NPIIRTVKSV GMIAGGTGIT PMLQVIRAIM KDPDDHTVCH LLFANQTEKD ILLRPELEEL RNKHSARFKL WYTLDRAPEA WDYGQGFVNE EMIRDHLPPP EEEPLVLMCG PPPMIQYACL PNLDH
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Target Information
CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B5R; DIA1; Diaphorase-1; Diaphorase1; mutant NADH-cytochrome b5 reductase; NADH cytochrome b5 reductase (EC 1.6.2.2); NADH-cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form; unnamed protein product
Gene Aliases: B5R; CYB5R3; DIA1
UniProt ID: (Human) P00387
Entrez Gene ID: (Human) 1727
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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