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Invitrogen
PFKM Polyclonal Antibody
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Product Details
PA5-51687
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PFKM. Recombinant protein control fragment (Product #RP-101891).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CVQVTKDVTK AMDEKKFDEA LKLRGRSFMN NWEVYKLLAH VRPPVSKSGS HTVAVMNVGA PAAGMNAAVR STVRIGLIQG NRVLVVHDGF EGLAKGQIEE AGWSYVGGWT GQGGSKLGTK RTLPKKSFEQ ISA
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255|HAMAP-Rule:MF_03184}; ATP-PFK; ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}; PFK-A; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase muscle; phosphofructokinase, polypeptide X; phosphofructokinase-A; phosphofructokinase-M; Phosphohexokinase; phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184}; protein phosphatase 1, regulatory subunit 122
Gene Aliases: ATP-PFK; GSD7; PFK-1; PFK-A; Pfk-M; PFK1; PFKA; PFKM; PFKX; PPP1R122
UniProt ID: (Human) P08237, (Rat) P47858
Entrez Gene ID: (Human) 5213, (Rat) 65152
6-phosphofructokinase activity
protein binding
ATP binding
protein C-terminus binding
kinase binding
identical protein binding
protein homodimerization activity
metal ion binding
fructose binding
phosphofructokinase activity
AMP binding
carbohydrate binding
fructose-6-phosphate binding
carbohydrate kinase
kinase
transferase
metabolite interconversion enzyme
glycogen catabolic process
fructose 6-phosphate metabolic process
glycolytic process
positive regulation of insulin secretion
glucose homeostasis
muscle cell cellular homeostasis
carbohydrate phosphorylation
protein oligomerization
canonical glycolysis
glycolysis from storage polysaccharide through glucose-1-phosphate
cellular glucose homeostasis
fructose 1,6-bisphosphate metabolic process
protein homotetramerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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