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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FMNL3 Antibodies

          Invitrogen

          FMNL3 Polyclonal Antibody

          View all (5) FMNL3 antibodies

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          Cite FMNL3 Polyclonal Antibody

          • Antibody Testing Data (2)
          FMNL3 Antibody in Immunocytochemistry (ICC/IF)
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          FMNL3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          FMNL3 Antibody (PA5-51720) in ICC/IF

          Immunofluorescent staining of FMNL3 in human cell line A-431 using a FMNL3 Polyclonal Antibody (Product # PA5-51720) shows localization to plasma membrane, cytosol, the Golgi apparatus and vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          FMNL3 Antibody in Immunocytochemistry (ICC/IF)
          FMNL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FMNL3 Polyclonal Antibody

          Product Details

          PA5-51720

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human FMNL3. Recombinant protein control fragment (Product #RP-102030).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2641682

          Product Specific Information

          Immunogen sequence: LLDVKELGRG MELIRRECSI HDNSVLRNFL STNEGKLDKL QRDAKTAEEA YNAVVRYFGE SPKTTPPSVF FPVFVRFIRS YKEAEQENEA RKKQEEVMRE KQLAQEAKKL DAKTPSQRNK WQQQE

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          Target Information

          FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Formin homology 2 domain-containing protein 3; formin-like 3; Formin-like protein 3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3

          View more View less

          Gene Aliases: FHOD3; FMNL3; FRL2; KIAA2014; WBP-3; WBP3

          View more View less

          UniProt ID: (Human) Q8IVF7

          View more View less

          Entrez Gene ID: (Human) 91010

          View more View less

          Function(s)
          actin binding Rho GTPase binding GTPase activating protein binding
          Process(es)
          angiogenesis cytoskeleton organization regulation of cell shape cell migration actin cytoskeleton organization
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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