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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GDSPKIDLAG SSLSGILDKD LSDRSNDIDL EGFDSVVSST EKLSHPTTSR PKATGRRPPS QSLTSSSLSS PDIFDSPSPE EDKEEHISLA HRGVDASKKT SKTVTISQVS DNKASLP
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cbl-interacting protein of 85 kDa; CD2-binding protein 3; CD2BP3; HSB-1; Human Src family kinase-binding protein 1; Regulator of ubiquitous kinase; Ruk; SH3 domain-containing kinase-binding protein 1; SH3-containing, expressed in tumorigenic astrocytes
Gene Aliases: 1200007H22Rik; 1700125L08Rik; 5830464D22Rik; AI447724; CIN85; IN85; Ruk; Seta; SH3KBP1
UniProt ID: (Mouse) Q8R550
Entrez Gene ID: (Mouse) 58194
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