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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GDSPKIDLAG SSLSGILDKD LSDRSNDIDL EGFDSVVSST EKLSHPTTSR PKATGRRPPS QSLTSSSLSS PDIFDSPSPE EDKEEHISLA HRGVDASKKT SKTVTISQVS DNKASLP
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-Cbl-interacting protein; cbl-interacting protein of 85 kDa; CD2-binding adaptor protein; CD2-binding protein 3; cell growth-inhibiting gene 10 protein; human Src family kinase-binding protein 1; MIG18; migration-inducing gene 18; regulator of ubiquitous kinase; Ruk(deltaA) protein; Ruk(h) protein; Ruk(l) protein; Ruk(m1) protein; Ruk(m3) protein; Ruk(t) protein; Ruk(xl) protein; SH3-containing, expressed in tumorigenic astrocytes; SH3-domain kinase binding protein 1; Src family kinase-binding protein 1; src-related kinase binding protein-1; src-related kinase binding protein-1; HSB-1; unnamed protein product
Gene Aliases: 1200007H22Rik; 1700125L08Rik; 5830464D22Rik; AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; IN85; MIG18; Ruk; Seta
UniProt ID: (Human) Q96B97, (Mouse) Q8R550
Entrez Gene ID: (Human) 30011, (Mouse) 58194
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