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Invitrogen
TRIP13 Polyclonal Antibody
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Product Details
PA5-52193
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRIP13. Recombinant protein control fragment (Product #RP-89294).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: STAKKEDINL SVRKLLNRHN IVFGDYTWTE FDEPFLTRNV QSVSIIDTEL KVKDSQPIDL SACTVALHIF QLNEDGPSSE NLEEETENII AANHWVLPAA EFHGLWDSLV YDVEVKSH
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 16E1-BP; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; Human papillomavirus type 16 E1 protein-binding protein; Pachytene checkpoint protein 2 homolog; Thyroid hormone receptor interactor 13; thyroid receptor interacting protein 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13
Gene Aliases: 16E1BP; PCH2; TRIP13
UniProt ID: (Human) Q15645
Entrez Gene ID: (Human) 9319
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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