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Invitrogen
AKAP4 Polyclonal Antibody
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Product Details
PA5-52230
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AKAP4. Recombinant protein control fragment (Product #RP-92144).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SALKLIQYHL TQQTKGKDTC EEDCPGSTMG YMAQSTQYEK CGGGQSAKAL SVKQLESHRA PGPSTCQKEN QHLDSQKMDM SNIVLMLIQK LLNENPFKCE DPCEGENKCS EPRASKAASM SNRSDKAEEQ CQEHQELDCT SGMKQ
Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 65%.
Target Information
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A kinase (PRKA) anchor protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 82; AKAP-4; AKAP4; cancer/testis antigen 99; HI; Major sperm fibrous sheath protein; PRKA4; protein kinase A anchoring protein 4; Protein kinase A-anchoring protein 4; testis-specific gene HI
Gene Aliases: AKAP 82; AKAP-4; AKAP4; AKAP82; CT99; FSC1; hAKAP82; HI; p82; PRKA4
UniProt ID: (Human) Q5JQC9
Entrez Gene ID: (Human) 8852
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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