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Invitrogen
TAF5 Polyclonal Antibody
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Product Details
PA5-52266
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAF5. Recombinant protein control fragment (Product #RP-89362).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TVVSGSASGP AAPGKVGSVA VEDQPDVSAV LSAYNQQGDP TMYEEYYSGL KHFIECSLDC HRAELSQLFY PLFVHMYLEL VYNQHENEAK SFFEKFHGDQ ECYYQDDLRV LSSLTKKEHM KGNETMLDF
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
Target Information
TFIID is a general transcription factor which initiates preinitiation complex assembly through direct interaction with the TATA promoter element. It is a multisubunit complex consisting of a small TATA-binding polypeptide andother TATA-binding protein (TBP)-associated factors (TAFs). Although native TFIID can mediate both activator-independent (basal) and activator-dependent transcription in reconstituted systems, TBP can mediate only basal transcription. TAF II p100 (TBP-associated factor II100), also known as TAF5 or TAFII100, is the third largest subunit of human TFIID. It contains six WD40 repeats at the C-terminus and has an N-terminus capable of forming a flexible dimer. TAF II p100 plays an important role in forming the scaffold that is crucial for the assembly of the TFIID complex. TAF II p100 may also be involved in the stabilization of TAF interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TAF(II)100; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; TATA box binding protein (TBP)-associated factor 2D; TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD; transcription initiation factor TFIID 100 kD subunit; Transcription initiation factor TFIID 100 kDa subunit; Transcription initiation factor TFIID subunit 5; unnamed protein product
Gene Aliases: TAF(II)100; TAF2D; TAF5; TAFII-100; TAFII100
UniProt ID: (Human) Q15542
Entrez Gene ID: (Human) 6877
regulation of DNA repair
DNA-templated transcription, initiation
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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