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Invitrogen
TAF7 Polyclonal Antibody
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Product Details
PA5-52296
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAF7. Recombinant protein control fragment (Product #RP-89412).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ISSPGMSGHR QGHDSLEHDE LREIFNDLSS SSEDEDETQH QDEEDINIID TEEDLERQLQ DKLNESDEQH QENEGTNQLV MGIQKQIDNM KGKLQETQDR AKRQEDLIMK VENLALKN
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA polymerase II TBP-associated factor subunit F; TAF(II)55; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; TAFII-55; TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD; TBP-associated factor F; transcription factor IID subunit TAFII55; Transcription initiation factor TFIID 55 kDa subunit; Transcription initiation factor TFIID subunit 7; transcription initiation factor TFIID, 55 kDa subunit; unnamed protein product
Gene Aliases: TAF2F; TAF7; TAFII55
UniProt ID: (Human) Q15545
Entrez Gene ID: (Human) 6879
transcription regulatory region sequence-specific DNA binding
TFIIH-class transcription factor binding
protein binding
obsolete general RNA polymerase II transcription factor activity
histone acetyltransferase binding
vitamin D receptor binding
thyroid hormone receptor binding
protein heterodimerization activity
H3K27me3 modified histone binding
P-TEFb complex binding
DNA-binding transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
spermine transport
regulation of DNA repair
chromatin organization
DNA-templated transcription, initiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
negative regulation of protein kinase activity
intracellular estrogen receptor signaling pathway
mRNA transcription from RNA polymerase II promoter
negative regulation of MHC class I biosynthetic process
negative regulation of MHC class II biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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