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Invitrogen
RBM14 Polyclonal Antibody
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Product Details
PA5-52314
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RBM14. Recombinant protein control fragment (Product #RP-89418).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TQSSASLAAS YAAQQHPQAA ASYRGQPGNA YDGAGQPSAA YLSMSQGAVA NANSTPPPYE RTRLSPPRAS YDDPYKKAVA MSKRYGSDRR LAELSDYRRL SESQLSFRRS PTKSSLDYRR LPDAHSDYAR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CoAA; CoAM; CoAR; Paraspeckle protein 2; PSP2; rna-binding; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; synaptotagmin interacting protein; Synaptotagmin-interacting protein; SYT-interacting protein; transmembrane protein 137; unnamed protein product
Gene Aliases: 1300007E16Rik; COAA; p16; p16K; PSP2; RBM14; SIP; Sytip; SYTIP1; TMEM137
UniProt ID: (Human) Q96PK6, (Mouse) Q8C2Q3
Entrez Gene ID: (Human) 10432, (Mouse) 56275
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
activation of innate immune response
immune system process
apoptotic process
gastrulation
response to hormone
gene expression
innate immune response
positive regulation of gene expression, epigenetic
positive regulation of transcription from RNA polymerase II promoter
negative regulation of centriole replication
centriole assembly
regulation of response to DNA integrity checkpoint signaling
transcription, DNA-templated
regulation of transcription, DNA-templated
histone deacetylation
SMAD protein signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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