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Invitrogen
PAXIP1 Polyclonal Antibody
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Product Details
PA5-52327
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PAXIP1. Recombinant protein control fragment (Product #RP-89488).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EEEEEVENEE QDSQNEGSTD EKSSPASSQE GSPSGDQQFS PKSNTEKSKG ELMFDDSSDS SPEKQERNLN WTPAEVPQLA AAKRRLPQGK EPGLINLCAN VPPVPGNILP PEVRGNLMAA GQNLQSSERS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 50%.
Target Information
This gene is a member of the paired box gene family and encodes a nuclear protein with six BRCT domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ41049; PAX interacting (with transcription-activation domain) protein 1; PAX transactivation activation domain-interacting protein; PAX transcription activation domain interacting protein 1 like; PAX-interacting protein 1; protein encoded by CAG trinucleotide repeats
Gene Aliases: CAGF28; CAGF29; PACIP1; PAXIP1; PAXIP1L; PTIP; TNRC2
UniProt ID: (Human) Q6ZW49
Entrez Gene ID: (Human) 22976
positive regulation of histone H3-K36 methylation
vasculogenesis
double-strand break repair via nonhomologous end joining
DNA recombination
transcription, DNA-templated
response to ionizing radiation
DNA damage response, signal transduction by p53 class mediator
positive regulation of protein ubiquitination
positive regulation of histone acetylation
endothelial cell migration
positive regulation of isotype switching
histone H3-K4 methylation
positive regulation of histone H3-K4 methylation
positive regulation of transcription initiation from RNA polymerase II promoter
adipose tissue development
chorion development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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