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Invitrogen
Plexin-A1 Polyclonal Antibody
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Product Details
PA5-52444
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLXNA1. Recombinant protein control fragment (Product #RP-90138).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QDFNQPLGGT VTIEGTPLFV DKDDGLTAVA AYDYRGRTVV FAGTRSGRIR KILVDLSNPG GRPALAYESV VAQEGSPILR DLVLSPNHQY LYAMTEKQVT
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plexin 1; Plexin-A1; Semaphorin receptor NOV; unnamed protein product
Gene Aliases: DWOPNED; NOV; NOVP; PLEXIN-A1; PLXN1; PLXNA1
UniProt ID: (Human) Q9UIW2
Entrez Gene ID: (Human) 5361
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
synapse assembly
regulation of smooth muscle cell migration
olfactory nerve formation
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
regulation of cell migration
dichotomous subdivision of terminal units involved in salivary gland branching
semaphorin-plexin signaling pathway
neuron projection guidance
neuron projection extension
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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