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Invitrogen
EAF2 Polyclonal Antibody
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Product Details
PA5-52557
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EAF2. Recombinant protein control fragment (Product #RP-89676).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GFSHLDRRER VLKLGESFEK QPRCAFHTVR YDFKPASIDT SSEGYLEVGE GEQVTITLPN IEGSTPPVTV FKGSKKPYLK ECILIINHDT GECRL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 89%.
Target Information
EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELL-associated factor 2; Testosterone-regulated apoptosis inducer and tumor suppressor protein
Gene Aliases: BM-040; BM040; EAF2; TRAITS; U19
UniProt ID: (Human) Q96CJ1
Entrez Gene ID: (Human) 55840
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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