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          • Primary Antibodies ›
          • MGST2 Antibodies

          Invitrogen

          MGST2 Polyclonal Antibody

          View all (8) MGST2 antibodies

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          Cite MGST2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          MGST2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MGST2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          MGST2 Antibody (PA5-52732) in IHC (P)

          Immunohistochemical analysis of MGST2 in human liver using MGST2 Polyclonal Antibody (Product # PA5-52732) shows strong cytoplasmic positivity in hepatocytes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MGST2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MGST2 Antibody in Western Blot (WB)
          MGST2 Polyclonal Antibody

          Product Details

          PA5-52732

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human MGST2. Recombinant protein control fragment (Product #RP-90627).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2643944

          Product Specific Information

          Immunogen sequence: LKYKVTPPAV TGSPEFERVF RAQQNCVEFY PIF

          Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 76%.

          Target Information

          MGST2 (Microsomal glutathione S-transferase 2) is a 147 amino acid protein encoded by the human gene MGST2. MGST2 can catalyze the production of LTC4 (leukotriene C4) from LTA4 (leukotriene A4) and reduced glutathione. It can also catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione. MSGT2 is a multi-pass membrane protein found as a homodimer. MGST2 belongs to the MAPEG family and is expressed in liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. It has very low expression in lung, brain, placenta and bone marrow. Also, MGST2 is the only GST expressed in human umbilical vein endothelial cells (HUVECs).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ27438; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; MGC14097; MGST2; Microsomal glutathione S-transferase 2; Microsomal glutathione S-transferase II; Microsomal GST-2; Microsomal GST-II

          View more View less

          Gene Aliases: GST2; MGST-II; MGST2

          View more View less

          UniProt ID: (Human) Q99735

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          Entrez Gene ID: (Human) 4258

          View more View less

          Function(s)
          glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity protein binding enzyme activator activity oxidoreductase activity transferase activity lyase activity identical protein binding glutathione binding
          Process(es)
          lipid metabolic process leukotriene metabolic process glutathione biosynthetic process leukotriene biosynthetic process response to lipopolysaccharide carboxylic acid biosynthetic process membrane lipid catabolic process positive regulation of inflammatory response cellular oxidant detoxification
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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