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Invitrogen
ALOX15 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-53097
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ALOX15. Recombinant protein control fragment (Product #RP-90629).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RTVGEDPQGL FQKHREEELE ERRKLYRWGN WKDGLILNMA GAKLYDLPVD ERFLEDKRVD FEVSLAKGLA DLAIKDSLNV LTCWKDLDDF NRIFWCGQSK LAERVRDSWK EDALFGYQ
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 66%.
Target Information
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12/15-lipoxygenase; 15-lipooxygenase-1; 15-lipoxygenase; 15-lipoxygenase type 1; 15-LOX type 1; 15-LOX2; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase; hepoxilin A3 synthase Alox15; linoleate 13S-lipoxygenase; unnamed protein product
Gene Aliases: 12-LOX; 15-LOX; 15-LOX-1; LOG15
UniProt ID: (Human) P16050
Entrez Gene ID: (Human) 246
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
arachidonate 15-lipoxygenase activity
hydroperoxy icosatetraenoate isomerase activity
hydroperoxy icosatetraenoate dehydratase activity
ossification
negative regulation of adaptive immune response
lipid metabolic process
phosphatidylethanolamine biosynthetic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of actin filament polymerization
lipid oxidation
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
long-chain fatty acid biosynthetic process
apoptotic cell clearance
linoleic acid metabolic process
regulation of inflammatory response
hepoxilin biosynthetic process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin biosynthetic process
lipoxin A4 biosynthetic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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