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Invitrogen
ALOX15 Polyclonal Antibody
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Product Details
PA5-53097
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ALOX15. Recombinant protein control fragment (Product #RP-90629).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RTVGEDPQGL FQKHREEELE ERRKLYRWGN WKDGLILNMA GAKLYDLPVD ERFLEDKRVD FEVSLAKGLA DLAIKDSLNV LTCWKDLDDF NRIFWCGQSK LAERVRDSWK EDALFGYQ
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 66%.
Target Information
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12-LOX; 12/15-lipoxygenase; 15-lipooxygenase-1; 15-lipoxygenase; 15-lipoxygenase type 1; 15-LOX; 15-LOX type 1; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15; unnamed protein product
Gene Aliases: 12-LOX; 15-LOX; 15-LOX-1; ALOX15; LOG15
UniProt ID: (Human) P16050
Entrez Gene ID: (Human) 246
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
lipid binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
arachidonate 15-lipoxygenase activity
dioxygenase activity
ossification
negative regulation of adaptive immune response
lipid metabolic process
fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of actin filament polymerization
lipid oxidation
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
long-chain fatty acid biosynthetic process
apoptotic cell clearance
linoleic acid metabolic process
regulation of inflammatory response
hepoxilin biosynthetic process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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