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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DFKAPNTETE PLLTWKKAQE TVPWNIILLL GGGFAMAKGC EESGLSVWIG GQLHPLENVP
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hNaDC3; membrane transporter responsible for the transport of tricarboxylic acid cycle intermediates; Na(+)-coupled carboxylate transporter 3; naDC-3; NADC3; integral membrane transporter; sodium-dependent high affinity dicarboxylate transporter 3; unnamed protein product
Gene Aliases: ARLIAK; NaC3; NADC3; SDCT2
UniProt ID: (Human) Q8WWT9
Entrez Gene ID: (Human) 64849
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