Immunohistochemical staining of ABI3 in human tonsil and pancreas tissues using ABI3 Polyclonal Antibody (Product # PA5-53592). Corresponding ABI3 RNA-seq data are presented for the same tissues.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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ABI3 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of ABI3 demonstrates antibody specificity. Immunohistochemical analysis of ABI3 using anti-ABI3 Polyclonal Antibody (Product # PA5-53592), shows significant staining of ABI3 in human tonsil and shows minimal or weak staining in human pancreas tissues. The relative expression levels of ABI3 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image ABI3 Polyclonal Antibody

Product Details

PA5-53592

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ABI3. Recombinant protein control fragment (Product #RP-90723).

3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

20 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2637567

Product Specific Information

Immunogen sequence: AYQVGNLAGH TLRMLDLQGA ALRQVEARVS TLGQMVNMHM EKVARREIGT LATVQRLPPG QKVIAPENLP PLTPYCRRPL NFGCLDDIGH GIKDLSTQLS RT

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.

Target Information

Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: new molecule including SH3

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Gene Aliases: NESH; SSH3BP3

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UniProt ID: (Human) Q9P2A4

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Entrez Gene ID: (Human) 51225

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Function(s)

protein binding signaling adaptor activity identical protein binding actin filament binding

Process(es)

neuron migration defense response to tumor cell negative regulation of lamellipodium assembly peptidyl-tyrosine phosphorylation actin cytoskeleton organization regulation of cell migration cell projection morphogenesis regulation of dendritic spine morphogenesis modification of postsynaptic actin cytoskeleton regulation of postsynaptic density assembly negative regulation of ruffle assembly negative regulation of protein localization to plasma membrane positive regulation of cellular senescence

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ABI3 Polyclonal Antibody

ABI3 Antibody (PA5-53592) in IHC

Product Details

PA5-53592

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Amount

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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