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Invitrogen
ADCY10 Polyclonal Antibody
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Product Details
PA5-53633
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ADCY10. Recombinant protein control fragment (Product #RP-90978).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RNTTYIVIGA VQPNDISNKI CLDLNVSCIS KELDSYLGEG SCGIPFYCEE LLKNLEHHEV LVFQQTESEE KTNRTWNNLF KYSIKLTEKL NMVTLHSDKE SEEVCHLTSG VRLKNLSPPT SLKEISLI
Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 67%.
Target Information
SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3',5'-cyclic AMP synthetase; adenylate cyclase 10, soluble; Adenylate cyclase homolog; Adenylate cyclase type 10; AH-related protein; ATP pyrophosphate-lyase; epididymis secretory sperm binding protein Li 7a; Germ cell soluble adenylyl cyclase; hsAC; RP1-313L4.2; SAC; Testicular soluble adenylyl cyclase; testicular soluble adenylyl cyclase (SAC); unnamed protein product
Gene Aliases: ADCY10; HCA2; HEL-S-7a; hsAC; SAC; SACI; Sacy
UniProt ID: (Human) Q96PN6
Entrez Gene ID: (Human) 55811
epithelial cilium movement
glucose catabolic process
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
spermatogenesis
spermatid development
cyclic nucleotide biosynthetic process
positive regulation of cardiac muscle hypertrophy
positive regulation of cardiac muscle cell apoptotic process
negative regulation of mitochondrial membrane potential
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of axon extension
positive regulation of ossification
positive regulation of glycogen catabolic process
positive regulation of mitochondrial depolarization
regulation of membrane repolarization
neuron projection retraction
negative regulation of cardiac muscle cell contraction
regulation of mitophagy
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of reactive oxygen species biosynthetic process
positive regulation of reactive oxygen species biosynthetic process
positive regulation of protein targeting to mitochondrion
positive regulation of vascular associated smooth muscle cell apoptotic process
neuron projection extension
neuron projection maintenance
mitochondrial ATP transmembrane transport
positive regulation of ATP biosynthetic process
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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