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Invitrogen
FAM161B Polyclonal Antibody
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Product Details
PA5-53931
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAM161B. Recombinant protein control fragment (Product #RP-88870).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GSRQIFPPES FADTEAGEEL SGDGLVLPRA SKLDEFLSPE EEIDSTSDST GSIYQNLQEL KQKGRWCLLE SLFQSDPESD ENLSEDEEDL ESFFQDKDRG MVQVQCPQAL RCGSTRRCSS LNNLPSNIPR PQTQPPS
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
Target Information
FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 161, member B; Protein FAM161B
Gene Aliases: c14_5547; C14orf44; FAM161B
UniProt ID: (Human) Q96MY7
Entrez Gene ID: (Human) 145483
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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