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Invitrogen
CROT Polyclonal Antibody
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Product Details
PA5-53985
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CROT. Recombinant protein control fragment (Product #RP-92590).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KVPVHKVGNT PLDMNQFRML FSTCKVPGIT RDSIMNYFRT ESEGRSPNHI VVLCRGRAFV FDVIHEGCLV TPPELLRQLT YIHKKCHSEP DGPGIAALTS EERTRWAKAR EYLIGLD
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 86%.
Target Information
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
Gene Aliases: COT; CROT
UniProt ID: (Human) Q9UKG9
Entrez Gene ID: (Human) 54677
generation of precursor metabolites and energy
fatty acid metabolic process
fatty acid beta-oxidation
carnitine metabolic process
response to organonitrogen compound
fatty acid transport
coenzyme A metabolic process
fatty acid beta-oxidation using acyl-CoA oxidase
response to drug
medium-chain fatty acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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