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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ERC1 Antibodies

          Invitrogen

          ERC1 Polyclonal Antibody

          View all (9) ERC1 antibodies

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          Cite ERC1 Polyclonal Antibody

          • Antibody Testing Data (2)
          ERC1 Antibody in Immunocytochemistry (ICC/IF)
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          ERC1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          ERC1 Antibody (PA5-54011) in ICC/IF

          Immunofluorecent analysis of ERC1 in human cell line U-251 MG using ERC1 Polyclonal Antibody (Product # PA5-54011). Staining shows localization to plasma membrane and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ERC1 Antibody in Immunocytochemistry (ICC/IF)
          ERC1 Antibody in Western Blot (WB)
          ERC1 Polyclonal Antibody

          Product Details

          PA5-54011

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ERC1. Recombinant protein control fragment (Product #RP-92554).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2641088

          Product Specific Information

          Immunogen sequence: TPKSTMTLGR SGGRLPYGVR MTAMGSSPNI ASSGVASDTI AFGEHHLPPV SMASTVPHSL RQARDNTIMD LQTQLKEVLR ENDLLRKDVE VK

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          Target Information

          The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: ELKS/Rab6-interacting/CAST family member 1; ERC-1; FLJ31750; MGC12974; OTTHUMP00000160633; RAB6 interacting protein 2; Rab6-interacting protein 2

          View more View less

          Gene Aliases: Cast2; ELKS; ERC-1; ERC1; KIAA1081; RAB6IP2

          View more View less

          UniProt ID: (Human) Q8IUD2

          View more View less

          Entrez Gene ID: (Human) 23085

          View more View less

          Function(s)
          protein binding Rab GTPase binding PDZ domain binding leucine zipper domain binding cadherin binding involved in cell-cell adhesion membrane traffic protein
          Process(es)
          regulation of transcription, DNA-templated I-kappaB phosphorylation multicellular organism development protein transport retrograde transport, endosome to Golgi positive regulation of NF-kappaB transcription factor activity cell-cell adhesion
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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