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Invitrogen
ASZ1 Polyclonal Antibody
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Product Details
PA5-54234
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ALP1. Recombinant protein control fragment (Product #RP-92763).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DGHTQVVALL VAHGAEVNTQ DENGYTALTW AARQGHKNIV LKLLELGANK MLQTKDGKMP SEIAKRNKHH EIFNLLSFTL NPLEGKLQQL TKED
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.
Target Information
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein; unnamed protein product
Gene Aliases: ALP1; ANKL1; ASZ1; C7orf7; CT1.19; GASZ; Orf3
UniProt ID: (Human) Q8WWH4
Entrez Gene ID: (Human) 136991
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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