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Invitrogen
AASS Polyclonal Antibody
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Product Details
PA5-54260
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AASS. Recombinant protein control fragment (Product #RP-92604).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PVSMDICKQE EKLGFLVAKQ DLVISLLPYV LHPLVAKACI TNKVNMVTAS YITPALKELE KSVEDAGITI IGELGLDPGL DHMLAMETID KAKEVGATIE SYISYCGGLP APEHSNNPLR YK
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
Target Information
AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-aminoadipate semialdehyde synthase; Alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipic semialdehyde synthase; LKR/SDH; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase
Gene Aliases: AASS; LKR/SDH; LKRSDH; LORSDH
UniProt ID: (Human) Q9UDR5
Entrez Gene ID: (Human) 10157
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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