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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DLALIPDVDI DSDGVFKYVL IRVHSAPRSG APAAESKEIV RGYKWAEYHA DIYDKVSGDM QKQGCDCECL GGGRISHQSQ DKKIHVYGYS MAYGPAQHAI STEKIKAKYP DYE
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 132P; JANA; PHP14; protein histidine phosphatase; protein janus-A homolog; PTP-H1; PTPH1; sex-regulated protein janus-a
Gene Aliases: CGI-202; HEL-S-132P; HSPC141; PHP; PHP14
UniProt ID: (Human) Q9NRX4
Entrez Gene ID: (Human) 29085
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