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Invitrogen
RNF135 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-54457
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RNF135. Recombinant protein control fragment (Product #RP-93486).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LSILGKAFSS GVDLSMASPK LVTSDTAAGK IRDILHDLEE IQEKLQESVT WKEAPEAQMQ GELLEAPSSS SCPLPDQSHP ALRRASRFAQ WAIHPTFNLK
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 49%.
Target Information
The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC13061; RIG-I E3 ubiquitin ligase; RING finger protein leading to RIG-I activation; RING-type E3 ubiquitin transferase RNF135; unnamed protein product
Gene Aliases: L13; MMFD; REUL; Riplet
UniProt ID: (Human) Q8IUD6
Entrez Gene ID: (Human) 84282
protein polyubiquitination
free ubiquitin chain polymerization
protein ubiquitination
positive regulation of interferon-beta production
RIG-I signaling pathway
innate immune response
regulation of innate immune response
protein homooligomerization
protein K63-linked ubiquitination
antiviral innate immune response
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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